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Search Results for " thyrotropin receptor "

11

Compounds

Cat No. Product Name Synonyms Targets
T12192 NCGC00229600 Others , TSH Receptor
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
T12073 ML-109 TSH Receptor
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)
T6956 Protirelin Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF Thyroid hormone receptor(THR) , Endogenous Metabolite
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
T5383 D3-βArr NCGC00379308 TSH Receptor
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
T29087 VA-K-14 hydrochloride VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl TSH Receptor
VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogate...
T13216 TSHR antagonist S37 TSH Receptor
TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
T13072 Taltirelin acetate TA-0910 acetate Thyroid hormone receptor(THR)
Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).
T13217 TSHR antagonist S37a Others
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy.
T38226 TSHR antagonist S37b
TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1].
TP2011 JKC363 JKC 363
Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, atten...
T7590 Taltirelin TA-0910 Thyroid hormone receptor(THR)
Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].
TargetMol